Journal of Medicinal Chemistry

The Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action. Some specific areas that are appropriate include the following: -Design, synthesis, and biological evaluation of novel biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools. -Molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). Routine extensions of existing series that do not utilize novel chemical or biological approaches or do not add significantly to a basic understanding of the SAR of the series will normally not be accepted for publication. -Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes in the action of biologically active compounds. -Molecular biological studies (e.g., site-directed mutagenesis) of macromolecular targets that lead to an improved understanding of molecular recognition. -Computational studies that provide fresh insight into the SAR of compound series that are of current general interest or analysis of other available data that subsequently advance medicinal chemistry knowledge. -Substantially novel computational chemistry methods with demonstrated value for the identification, optimization, or target interaction analysis of bioactive molecules. -Effect of molecular structure on the distribution, pharmacokinetics, and metabolic transformation of biologically active compounds. This may include design, synthesis, and evaluation of novel types of prodrugs. -Novel methodology with broad application to medicinal chemistry, but only if the methods have been tested on relevant molecules.

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Category	Year	Quartile
Drug Discovery	1999	Q1
Drug Discovery	2000	Q1
Drug Discovery	2001	Q1
Drug Discovery	2002	Q1
Drug Discovery	2003	Q1
Drug Discovery	2004	Q1
Drug Discovery	2005	Q1
Drug Discovery	2006	Q1
Drug Discovery	2007	Q1
Drug Discovery	2008	Q1
Drug Discovery	2009	Q1
Drug Discovery	2010	Q1
Drug Discovery	2011	Q1
Drug Discovery	2012	Q1
Drug Discovery	2013	Q1
Drug Discovery	2014	Q1
Drug Discovery	2015	Q1
Drug Discovery	2016	Q1
Drug Discovery	2017	Q1
Drug Discovery	2018	Q1
Drug Discovery	2019	Q1
Drug Discovery	2020	Q1
Drug Discovery	2021	Q1
Drug Discovery	2022	Q1
Drug Discovery	2023	Q1
Molecular Medicine	1999	Q1
Molecular Medicine	2000	Q1
Molecular Medicine	2001	Q1
Molecular Medicine	2002	Q1
Molecular Medicine	2003	Q1
Molecular Medicine	2004	Q1
Molecular Medicine	2005	Q1
Molecular Medicine	2006	Q1
Molecular Medicine	2007	Q1
Molecular Medicine	2008	Q1
Molecular Medicine	2009	Q1
Molecular Medicine	2010	Q1
Molecular Medicine	2011	Q1
Molecular Medicine	2012	Q1
Molecular Medicine	2013	Q1
Molecular Medicine	2014	Q1
Molecular Medicine	2015	Q1
Molecular Medicine	2016	Q1
Molecular Medicine	2017	Q1
Molecular Medicine	2018	Q1
Molecular Medicine	2019	Q1
Molecular Medicine	2020	Q1
Molecular Medicine	2021	Q1
Molecular Medicine	2022	Q1
Molecular Medicine	2023	Q1

SJR

The SJR is a size-independent prestige indicator that ranks journals by their 'average prestige per article'. It is based on the idea that 'all citations are not created equal'. SJR is a measure of scientific influence of journals that accounts for both the number of citations received by a journal and the importance or prestige of the journals where such citations come from It measures the scientific influence of the average article in a journal, it expresses how central to the global scientific discussion an average article of the journal is.

Year	SJR
1999	1.809
2000	1.794
2001	1.660
2002	1.709
2003	1.771
2004	1.958
2005	1.941
2006	1.919
2007	2.119
2008	2.203
2009	2.034
2010	2.014
2011	2.252
2012	2.343
2013	2.298
2014	2.240
2015	2.446
2016	2.456
2017	2.567
2018	2.287
2019	2.093
2020	2.010
2021	1.888
2022	1.805
2023	1.986

Total Documents

Evolution of the number of published documents. All types of documents are considered, including citable and non citable documents.

Year	Documents
1999	563
2000	532
2001	496
2002	609
2003	619
2004	741
2005	873
2006	866
2007	721
2008	867
2009	816
2010	757
2011	703
2012	886
2013	793
2014	766
2015	684
2016	756
2017	685
2018	731
2019	701
2020	908
2021	1007
2022	904
2023	1025

Citations per document

This indicator counts the number of citations received by documents from a journal and divides them by the total number of documents published in that journal. The chart shows the evolution of the average number of times documents published in a journal in the past two, three and four years have been cited in the current year. The two years line is equivalent to journal impact factor ™ (Thomson Reuters) metric.

Cites per document	Year	Value
Cites / Doc. (4 years)	1999	4.188
Cites / Doc. (4 years)	2000	4.196
Cites / Doc. (4 years)	2001	4.290
Cites / Doc. (4 years)	2002	4.669
Cites / Doc. (4 years)	2003	4.793
Cites / Doc. (4 years)	2004	5.429
Cites / Doc. (4 years)	2005	5.458
Cites / Doc. (4 years)	2006	6.096
Cites / Doc. (4 years)	2007	5.303
Cites / Doc. (4 years)	2008	5.403
Cites / Doc. (4 years)	2009	5.374
Cites / Doc. (4 years)	2010	5.450
Cites / Doc. (4 years)	2011	5.739
Cites / Doc. (4 years)	2012	6.004
Cites / Doc. (4 years)	2013	5.919
Cites / Doc. (4 years)	2014	5.995
Cites / Doc. (4 years)	2015	6.094
Cites / Doc. (4 years)	2016	6.201
Cites / Doc. (4 years)	2017	6.332
Cites / Doc. (4 years)	2018	6.466
Cites / Doc. (4 years)	2019	6.527
Cites / Doc. (4 years)	2020	6.945
Cites / Doc. (4 years)	2021	7.811
Cites / Doc. (4 years)	2022	7.477
Cites / Doc. (4 years)	2023	7.354
Cites / Doc. (3 years)	1999	4.188
Cites / Doc. (3 years)	2000	4.329
Cites / Doc. (3 years)	2001	4.407
Cites / Doc. (3 years)	2002	4.773
Cites / Doc. (3 years)	2003	4.841
Cites / Doc. (3 years)	2004	5.256
Cites / Doc. (3 years)	2005	5.536
Cites / Doc. (3 years)	2006	6.105
Cites / Doc. (3 years)	2007	5.315
Cites / Doc. (3 years)	2008	5.341
Cites / Doc. (3 years)	2009	5.265
Cites / Doc. (3 years)	2010	5.352
Cites / Doc. (3 years)	2011	5.870
Cites / Doc. (3 years)	2012	5.902
Cites / Doc. (3 years)	2013	6.018
Cites / Doc. (3 years)	2014	5.965
Cites / Doc. (3 years)	2015	6.006
Cites / Doc. (3 years)	2016	6.358
Cites / Doc. (3 years)	2017	6.597
Cites / Doc. (3 years)	2018	6.351
Cites / Doc. (3 years)	2019	6.457
Cites / Doc. (3 years)	2020	6.853
Cites / Doc. (3 years)	2021	7.924
Cites / Doc. (3 years)	2022	7.319
Cites / Doc. (3 years)	2023	7.403
Cites / Doc. (2 years)	1999	4.268
Cites / Doc. (2 years)	2000	4.299
Cites / Doc. (2 years)	2001	4.457
Cites / Doc. (2 years)	2002	4.662
Cites / Doc. (2 years)	2003	4.541
Cites / Doc. (2 years)	2004	5.269
Cites / Doc. (2 years)	2005	5.498
Cites / Doc. (2 years)	2006	6.069
Cites / Doc. (2 years)	2007	5.141
Cites / Doc. (2 years)	2008	5.016
Cites / Doc. (2 years)	2009	5.045
Cites / Doc. (2 years)	2010	5.422
Cites / Doc. (2 years)	2011	5.626
Cites / Doc. (2 years)	2012	5.945
Cites / Doc. (2 years)	2013	5.798
Cites / Doc. (2 years)	2014	5.730
Cites / Doc. (2 years)	2015	6.007
Cites / Doc. (2 years)	2016	6.466
Cites / Doc. (2 years)	2017	6.437
Cites / Doc. (2 years)	2018	6.085
Cites / Doc. (2 years)	2019	6.166
Cites / Doc. (2 years)	2020	6.876
Cites / Doc. (2 years)	2021	7.669
Cites / Doc. (2 years)	2022	7.192
Cites / Doc. (2 years)	2023	6.953

Total Cites

Self-Cites

Evolution of the total number of citations and journal's self-citations received by a journal's published documents during the three previous years.
Journal Self-citation is defined as the number of citation from a journal citing article to articles published by the same journal.

Cites	Year	Value
Self Cites	1999	1031
Self Cites	2000	919
Self Cites	2001	844
Self Cites	2002	950
Self Cites	2003	912
Self Cites	2004	1071
Self Cites	2005	1413
Self Cites	2006	1468
Self Cites	2007	917
Self Cites	2008	1178
Self Cites	2009	961
Self Cites	2010	1061
Self Cites	2011	1082
Self Cites	2012	1206
Self Cites	2013	1160
Self Cites	2014	1101
Self Cites	2015	1099
Self Cites	2016	1220
Self Cites	2017	1088
Self Cites	2018	1180
Self Cites	2019	1162
Self Cites	2020	1501
Self Cites	2021	1868
Self Cites	2022	1787
Self Cites	2023	1964
Total Cites	1999	6981
Total Cites	2000	7004
Total Cites	2001	7303
Total Cites	2002	7594
Total Cites	2003	7924
Total Cites	2004	9061
Total Cites	2005	10900
Total Cites	2006	13633
Total Cites	2007	13181
Total Cites	2008	13138
Total Cites	2009	12920
Total Cites	2010	12866
Total Cites	2011	14323
Total Cites	2012	13433
Total Cites	2013	14118
Total Cites	2014	14208
Total Cites	2015	14685
Total Cites	2016	14260
Total Cites	2017	14553
Total Cites	2018	13495
Total Cites	2019	14024
Total Cites	2020	14507
Total Cites	2021	18543
Total Cites	2022	19146
Total Cites	2023	20868

External Cites per Doc

Cites per Doc

Evolution of the number of total citation per document and external citation per document (i.e. journal self-citations removed) received by a journal's published documents during the three previous years. External citations are calculated by subtracting the number of self-citations from the total number of citations received by the journal’s documents.

Cites	Year	Value
External Cites per document	1999	3.569
External Cites per document	2000	3.761
External Cites per document	2001	3.898
External Cites per document	2002	4.176
External Cites per document	2003	4.283
External Cites per document	2004	4.635
External Cites per document	2005	4.818
External Cites per document	2006	5.448
External Cites per document	2007	4.945
External Cites per document	2008	4.862
External Cites per document	2009	4.873
External Cites per document	2010	4.911
External Cites per document	2011	5.427
External Cites per document	2012	5.372
External Cites per document	2013	5.523
External Cites per document	2014	5.503
External Cites per document	2015	5.557
External Cites per document	2016	5.814
External Cites per document	2017	6.104
External Cites per document	2018	5.795
External Cites per document	2019	5.922
External Cites per document	2020	6.144
External Cites per document	2021	7.126
External Cites per document	2022	6.636
External Cites per document	2023	6.706
Cites per document	1999	4.188
Cites per document	2000	4.329
Cites per document	2001	4.407
Cites per document	2002	4.773
Cites per document	2003	4.841
Cites per document	2004	5.256
Cites per document	2005	5.536
Cites per document	2006	6.105
Cites per document	2007	5.315
Cites per document	2008	5.341
Cites per document	2009	5.265
Cites per document	2010	5.352
Cites per document	2011	5.870
Cites per document	2012	5.902
Cites per document	2013	6.018
Cites per document	2014	5.965
Cites per document	2015	6.006
Cites per document	2016	6.358
Cites per document	2017	6.597
Cites per document	2018	6.351
Cites per document	2019	6.457
Cites per document	2020	6.853
Cites per document	2021	7.924
Cites per document	2022	7.319
Cites per document	2023	7.403

% International Collaboration

International Collaboration accounts for the articles that have been produced by researchers from several countries. The chart shows the ratio of a journal's documents signed by researchers from more than one country; that is including more than one country address.

Year	International Collaboration
1999	24.16
2000	25.00
2001	27.02
2002	33.50
2003	30.69
2004	29.01
2005	31.73
2006	32.91
2007	31.76
2008	37.14
2009	34.93
2010	34.35
2011	39.12
2012	35.33
2013	39.22
2014	38.90
2015	38.74
2016	42.46
2017	43.36
2018	43.37
2019	44.37
2020	40.09
2021	37.84
2022	34.51
2023	31.51

Citable documents

Non-citable documents

Not every article in a journal is considered primary research and therefore "citable", this chart shows the ratio of a journal's articles including substantial research (research articles, conference papers and reviews) in three year windows vs. those documents other than research articles, reviews and conference papers.

Documents	Year	Value
Non-citable documents	1999	44
Non-citable documents	2000	69
Non-citable documents	2001	100
Non-citable documents	2002	83
Non-citable documents	2003	57
Non-citable documents	2004	15
Non-citable documents	2005	0
Non-citable documents	2006	1
Non-citable documents	2007	3
Non-citable documents	2008	4
Non-citable documents	2009	4
Non-citable documents	2010	4
Non-citable documents	2011	4
Non-citable documents	2012	5
Non-citable documents	2013	14
Non-citable documents	2014	19
Non-citable documents	2015	23
Non-citable documents	2016	15
Non-citable documents	2017	13
Non-citable documents	2018	11
Non-citable documents	2019	12
Non-citable documents	2020	14
Non-citable documents	2021	19
Non-citable documents	2022	24
Non-citable documents	2023	29
Citable documents	1999	1623
Citable documents	2000	1549
Citable documents	2001	1557
Citable documents	2002	1508
Citable documents	2003	1580
Citable documents	2004	1709
Citable documents	2005	1969
Citable documents	2006	2232
Citable documents	2007	2477
Citable documents	2008	2456
Citable documents	2009	2450
Citable documents	2010	2400
Citable documents	2011	2436
Citable documents	2012	2271
Citable documents	2013	2332
Citable documents	2014	2363
Citable documents	2015	2422
Citable documents	2016	2228
Citable documents	2017	2193
Citable documents	2018	2114
Citable documents	2019	2160
Citable documents	2020	2103
Citable documents	2021	2321
Citable documents	2022	2592
Citable documents	2023	2790

Cited documents

Uncited documents

Ratio of a journal's items, grouped in three years windows, that have been cited at least once vs. those not cited during the following year.

Documents	Year	Value
Uncited documents	1999	193
Uncited documents	2000	172
Uncited documents	2001	140
Uncited documents	2002	126
Uncited documents	2003	127
Uncited documents	2004	113
Uncited documents	2005	112
Uncited documents	2006	115
Uncited documents	2007	146
Uncited documents	2008	153
Uncited documents	2009	158
Uncited documents	2010	122
Uncited documents	2011	100
Uncited documents	2012	97
Uncited documents	2013	109
Uncited documents	2014	97
Uncited documents	2015	112
Uncited documents	2016	98
Uncited documents	2017	93
Uncited documents	2018	125
Uncited documents	2019	124
Uncited documents	2020	146
Uncited documents	2021	156
Uncited documents	2022	181
Uncited documents	2023	165
Cited documents	1999	1474
Cited documents	2000	1446
Cited documents	2001	1517
Cited documents	2002	1465
Cited documents	2003	1510
Cited documents	2004	1611
Cited documents	2005	1857
Cited documents	2006	2118
Cited documents	2007	2334
Cited documents	2008	2307
Cited documents	2009	2296
Cited documents	2010	2282
Cited documents	2011	2340
Cited documents	2012	2179
Cited documents	2013	2237
Cited documents	2014	2285
Cited documents	2015	2333
Cited documents	2016	2145
Cited documents	2017	2113
Cited documents	2018	2000
Cited documents	2019	2048
Cited documents	2020	1971
Cited documents	2021	2184
Cited documents	2022	2435
Cited documents	2023	2654

% Female Authors

Evolution of the percentage of female authors.

Year	Female Percent
1999	28.69
2000	28.45
2001	28.41
2002	30.61
2003	31.08
2004	30.97
2005	33.02
2006	32.85
2007	32.48
2008	34.90
2009	35.30
2010	35.30
2011	35.26
2012	34.95
2013	34.71
2014	36.18
2015	36.38
2016	34.93
2017	36.11
2018	35.29
2019	36.55
2020	36.86
2021	37.66
2022	37.46
2023	39.07

Documents cited by public policy (Overton)

Evolution of the number of documents cited by public policy documents according to Overton database.

Documents	Year	Value
Overton	1999	11
Overton	2000	20
Overton	2001	9
Overton	2002	16
Overton	2003	13
Overton	2004	19
Overton	2005	32
Overton	2006	32
Overton	2007	11
Overton	2008	20
Overton	2009	13
Overton	2010	19
Overton	2011	12
Overton	2012	20
Overton	2013	23
Overton	2014	25
Overton	2015	17
Overton	2016	16
Overton	2017	6
Overton	2018	10
Overton	2019	8
Overton	2020	14
Overton	2021	4
Overton	2022	3
Overton	2023	0